Volume 13 | Issue 11 |

 Abstract

Moringa oleifera, commonly known as drumstick, is a highly valued medicinal plant widely used in traditional and modern healthcare systems. Its leaves, pods, seeds, and flowers contain a rich profile of bioactive compounds such as flavonoids, phenolics, alkaloids, vitamins, and essential minerals. These constituents contribute to a broad range of pharmaceutical activities including antioxidant, anti-inflammatory, antimicrobial, antidiabetic, hepatoprotective, cardioprotective, and wound-healing effects. Recent studies highlight the potential of Moringa extracts as natural therapeutic agents with minimal side effects. Due to its strong phytochemical composition and versatile biological actions, Moringa oleifera is emerging as an important candidate for the development of herbal formulations and nutraceuticals.

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 Keywords

Moringa oleifera, Drumstick, Antioxidant, Anti-inflammatory, Antimicrobial, Hepatoprotective, Phytochemicals, Therapeutic potential.

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'Iron deficiency anaemia (IDA)' is considered to be one of the most significant public health problems, not only in adolescent girls and pregnant women living in low- and middle-income countries. While nutritional factors remain the dominant cause, genetic variations in iron metabolism can modify individual susceptibility and influence treatment response. This study investigated the prevalence and clinical impact of HFE (C282Y, H63D) and TFR2 gene polymorphisms in adolescent girls and expecting mothers from Rewa, Madhya Pradesh, India. A total of 520 participants (260 adolescent girls (between the ages of 10 and 18 years) and 260 expecting mothers (first or second trimester or less than 24 weeks during gestation) were assessed for 'hematological indices, serum ferritin, total iron-binding capacity (TIBC), and transferrin saturation (TS%)'. Genotyping was conducted using PCR-RFLP. The HFE C282Y variant was rare, but H63D heterozygosity was frequent and significantly associated with reduced ferritin and TS%, higher TIBC, and increased IDA risk. TFR2 variants showed limited direct association with IDA but may contribute through gene-gene interactions. These findings suggest that HFE H63D polymorphisms may exacerbate iron deficiency risk in high-demand physiological states, warranting genetic screening in anaemia control programs.

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HFE, TFR2, H63D, iron deficiency anaemia, gene polymorphism, iron homeostasis

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Ruskin Bond's 1975 novella A Flight of Pigeons is a work of historical fiction set in Shahjahanpur during British-ruled India, unfolding against the turbulent backdrop of the 1857 uprising. Bond revives the real-life story of Ruth Labadoor and her family, tracing their struggle for survival amid the violence that erupted during the First War of Indian Independence. Through his narrative, he captures the disorderly socio-political environment shaped by decades of colonial exploitation and domination. The novella portrays the unrest and uncertainty that marked the Sepoy Mutiny, revealing the anguish endured by both Indians and the British-origin families caught in its wake. Bond reconstructs this volatile period primarily through the experiences of Ruth and her mother, Mariam Labadoor, whose personal journeys highlight the broader cultural and psychological dislocation of the time. A Flight of Pigeons not only recounts political and historical upheaval but also explores the emotional and mental trauma inflicted on individuals living through the anti-colonial struggle.This paper examines how the socio-political, historical turbulence of 1857 is mirrored in the theme of this novella, and how the oppressive colonial hierarchy ultimately rebounded to create suffering for British families residing in and around Shahjahanpur. Our study also investigates the impact of the resistance movement on the psychological state of the colonised subjects.

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 Keywords

Political domination, Economic exploitation, Cultural conflict, Historical representation, Anti-colonial movements, Social unrest, Psychological trauma.

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Achieving reliable bonding between resin cements and high-strength ceramics, such as zirconia, is challenging due to the material's chemical inertness and absence of silica, which prevents traditional etching. This lack of etchability and inability to undergo silanization has led to ongoing debates among clinicians and researchers. Since zirconia restorations may occasionally fail to withstand dislodging forces, in current literature various alternative protocols have been suggested to improve bond strength between resin cements, tooth structures, and zirconia surfaces. For the long-term success and survival of of zirconia restorations, achieving sufficient bond strength is crucial to endure functional masticatory stresses. Consequently, the performance and bonding efficiency of these restorations are heavily dependent on the cementation procedure used. Despite extensive research, the literature on zirconia cementation presents conflicting results about the effectiveness of different luting agents, and no standardized protocol has been universally accepted. This review aims to categorize and evaluate the existing techniques designed to enhance the adhesion of zirconia to dental substrates. It also explores current trends in surface conditioning methods, seeking to identify approaches that offer consistent and reliable bonding outcomes. By analyzing these methods, this review aims to provide a clearer understanding of effective bonding strategies for zirconia restorations.

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 Keywords

Bonding, Resin cement, Surface treatment, Tribochemical silica, Zirconia

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Creative Commons Attribution 4.0 and The Open Definition

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Viksit Bharat @2047 is a vision of Hon'ble Prime Minister to make India a developed country by the year 2047, when India will celebrate its 100th year of independence. The core objective of the Viksit Bharat vision is to foster inclusive economic participation among all citizens. A key component of this initiative is the ambitious goal of elevating India to the rank of the world's third-largest economy within the next five years. Through a multidisciplinary approach, the paper examines key pathways to achieving this vision, encompassing economic growth through productivity, technological innovation for industrial safety, social equity for workforce, and environmental sustainability. The study highlights the necessity of industrial safety and health for economic growth, statutory provisions for creation of safety culture, uses of safety management for strategic investments in human capital, and the importance of governance reforms to foster inclusive development. By analyzing current challenges and leveraging opportunities in sectors such as education & training, healthcare, and digitalization, the paper provides actionable insights and recommendations.

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Viksit Bharat, Industrial/ Occupational safety, health and environment, Sustainable development, economic development, OSH Code

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Researcher aimed to compare the effectiveness of hot compression versus cold compression in reducing phlebitis among adults receiving intravenous therapy in Selected civil Hospital of Ludhiana, Punjab. A quantitative pre-experimental one-group pre-test post-test repeated measures design was adopted among 60 adults with IV infiltration. Phlebitis was assessed using a standardized phlebitis grading scale and pain was measured using the numerical pain rating scale. Findings revealed a significant reduction in phlebitis and pain scores in both groups, with cold compression demonstrating superior effectiveness. The study concludes that cold compression is more effective in reducing IV-induced phlebitis and can be implemented as a simple, affordable nursing intervention.

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Phlebitis, Hot Compression, Cold Compression, Intravenous Infiltration, Nursing Intervention

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This review paper presents a comprehensive examination of deep learning techniques employed for crop disease detection and classification using image-based methods. The introduction of advanced architectures such as Convolutional Neural Networks (CNNs) [1, 3], Residual Networks (ResNets), and Transfer Learning approaches [2] has significantly transformed agricultural disease management by enabling automated, high-accuracy plant disease identification.

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Deep Learning, CNN, Transfer Learning, Crop Disease Detection, Image Processing, Agriculture Technology

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Commentary on modern tragedy tends to revolve around two major arguments. First, is the question of whether there is modern tragedy and second, if yes, on what ground is the term justified. The argument is caused by the differing opinions as to the necessary ingredients of tragedy as identified by Aristotle. The focus of this discourse is to analyse to what extent Aristotle's Poetics has influenced tragic construction and theory of later periods. Poetics is not only the first significant work in dramatic theory but its major concepts and lines of arguments have influenced the development of theory and construction of tragedy throughout the centuries. An examination of the tragic conception from the time of the Greeks to the present reveals that tragedy has undergone a metamorphosis in definitions and experience. Based on this premise, this study emphasizes the diversity of the tragic conception and characteristics, its continuity and deviations. Even though there have been changes over the centuries in the concept of the tragic genre, its essence remains the same. For the purposes of this study, the researcher employs extensively, the Historical Research Methodology. Using the historical research methodology and Alfred Whitehead's Process Philosophy, this study submits that even though a precise and detailed discussion of the tragic forms begins with Aristotle, it did not end with him because Aristotle based his theory on the only examples available to him: The works of Aeschylus, Sophocles and Euripides. Many new types of serious plots ending in a catastrophe have been developed - types that Aristotle had no way of foreseeing. The Poetics should therefore be seen as Aristotle theorizing according to the great tendency of his time. His theory is descriptive and not prescriptive and should not be regarded as many generations following its appearance have: an unchallengeable law to be applied as whole to all tragic art without question. The study also proposes the Patho-Cathartic approach to the interpretation and determination of the tragic vision.

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Tragedy, poetics, Patho-cathartic, modernist, modernism, Aristotle

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The present study investigates the influence of NaCl stress on various organic metabolites in two varieties of Mulberry, Mysore Local and M5. The organic metabolites such as carbohydrates, proteins, total phenols, proline, total acid number and nitrogen contents were analyzed at different levels of (0.0, 0.25,0.5 and 1.0 Molar) NaCl stress in pot culture. Both the varieties showed moderate influence of salinity stress on organic constituents, there was slight inhibition in the proteins, sugars, Nitrogen and Total Acid number. Accumulation of proline and polyphenols act as osmoprotectants to overcome the NaCl stress. Among two cultivars variety M5 has got more salt tolerance capacity than the variety Mysore Local. The present study may help to screen salinity resistant cultivars.

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Salinity, Mulberry, Organic Metabolites, Nitrogen

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Creative Commons Attribution 4.0 and The Open Definition

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As the automotive industry aggressively looking to adopt sustainable materials, the design and analysis of environmentally friendly natural fiber composites is one of the promising solutions for reducing environmental impact. This study focuses on the development of a composite material derived from natural fibers (jute, hemp, sisal), specifically targeting its application in car front bumper beam. Static analysis was conducted using an ANSYS 21 to assess the tensile strength. Design of bumper beam created with the assistance of CATIA V5 R21. Finite element analysis (FEA) was employed to simulate the performance of the composite analyzing stress distribution and deformation under load. Conduct experiment using a Universal Testing Machine (UTM) and compare the FEA predictions to experimental predictions.

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 Keywords

Car front bumper, strength optimization, Natural composite material, Analysis, UTM.

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Creative Commons Attribution 4.0 and The Open Definition