Volume 12 | Issue 6 |

 Abstract

By the age of 50, approximatelyone-half of all males and females get androgenic alopecia (AGA), a condition characterized by progressive hair loss on the scalp, impacting self-esteem and physical appearance. AGA is attributed to the increased activity of 5-reductase enzyme in scalp hair follicles, leading to conversion of testosterone to dihydrotestosterone (DHT). Finasteride, a synthetic 4-aza-3-oxosteroid with low water solubility, inhibits this conversion, resulting in reduced DHT levels and hair loss mitigation.Although minoxidil, potassium channel opener and vasodilator, promotes hair growth by enhancing blood flow and nutrient delivery to the scalp,its precise mechanism for stimulating hair growth remains ambiguous and seems to operate separately from its vasodilatory effects. The investigations on both medications found that combining minoxidil and finasteride had a superior effect on hair loss than either therapy alone. Combining finasteride and minoxidil has shown superior efficacy compared to either drug alone in treating hair loss. To address limitations of current formulations, a topical preparation combining finasteride and minoxidil is needed, optimizing drug-to-scalp contact, reducing administration frequency, enhancing penetration, stimulating hair follicles, and improving hair growth. Utilizing niosomes, which act as localized drug depots, could prolong drug release and improve therapeutic outcomes while minimizing systemic adverse effects of finasteride.

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 Keywords

Androgenic alopecia, Testosterone, Dihydrotestosterone, Minoxidil, Finasteride, Vasodilator

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

This paper centers on the struggles and life of Rukmani, a rural woman. It depicts how a carefree young woman changes into a vulnerable and exploited woman attempting to support her family in the harsh and brutal city life. The study highlights the predicament, standing, and mindset of Indian women in the face of shifting social, political, economic, contemporary, and spiritual influences. It depicts women's actual struggles juggling tradition and modernity. Rukmani exhibits a genuine sense of tolerance by accepting hardship with an inner strength. She is a calm woman who accepts her unfavorable circumstances with grace and dignity, demonstrating her stoic acceptance of the unavoidable. The foundation of the indigenous people has been undermined by industrialization are compelled to abandon their belongings. They remain unbroken in their inner strength even in such circumstance due to her poverty, Rukmani fights against numerous obstacles, including prostitution, adultery, death, and feminism.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Industrialization, marginalization, rootlessness, alienation, fatalism, feminine sensibility.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Aouchithyanibhandhanam in Abhijnanashakuntalam

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Creative Commons Attribution 4.0 and The Open Definition

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Aouchithyanibhandhanam in Abhijnanashakuntalam

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Creative Commons Attribution 4.0 and The Open Definition

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Symbolism, as a mode of expression, often faces questions regarding its universality or cultural relativity. This research paper examines the ongoing debate surrounding universal symbolism versus cultural specificity, exploring the challenges and nuances involved in cross-cultural communication. With the assessment of the conflicting viewpoints by drawing on examples from various fields such as art, literature, and communication studies regarding this debate for the existence of universally understood symbols as well as the significance of cultural context in shaping symbolic meanings. Additionally, the paper discusses the implications of this debate on fostering mutual understanding in an increasingly interconnected global society. This academic exploration delves into the historical roots of these debates, tracing how scholars, anthropologists, and linguists have grappled with the question of whether symbols possess inherent, universal meanings or are inherently tied to the diverse cultural landscapes in which they emerge. Through an analysis of dynamic perspectives, this study aims to unravel the complexities of cross-cultural communication, providing insights into the evolving nature of these debates and their implications for understanding the intricacies of symbolic expression in a globalized world.

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 Keywords

Symbolic Interpretation, Cross-Cultural Communication, Universality, Cultural Specificity, Symbolic Analysis, Cultural Adaptation

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

This paper presents the design and implementation of an IoT-based automated water supply system aimed at addressing the issue of water scarcity for street animals in metropolitan areas during the summer months.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

ultrasonic , iot , automation , water management

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Bharati Mukherjee's novel "Jasmine" intricately weaves the narrative of its titular protagonist's journey of becomingness, which is marked by profound transformations in identity, geography, and cultural affiliations. This abstract presents a concise overview of the exploration of becomingness within the context of Mukherjee's work, analysing the factors that propel Jasmine's evolution and the broader themes it unveils.

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Plight, Women, Bharti Mukherjee, Jasmine

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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Creative Commons Attribution 4.0 and The Open Definition

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Mouth ulcer , gel

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Creative Commons Attribution 4.0 and The Open Definition

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Information technology is an important factor for any business environment where opting for the right technology is an essential because of the high competition persistence. To maintain accuracy and fast transaction it happens to be the required tool to sustain in the current competitive market. This study attempts to state the various technologies in logistics and supply chain, how it has impacted the industry and future perception toward information technology in logistics and supply chain management. Purposive sampling technique is used for collecting questionnaire from 110 respondents of southern region specifically confined to Tamil Nadu, Kerala and Karnataka.

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Logistics, Supply chain management, Information technology

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Creative Commons Attribution 4.0 and The Open Definition

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Abstract: Climate change disproportionately burdens rural women due to their social roles and limited access to resources. This paper explores the social challenges faced by rural women in the context of climate disruptions, highlighting the impact on livelihoods, health, and safety. It emphasizes the importance of recognizing women's agency and investing in their resilience for a more equitable and sustainable future.

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 Keywords

Climate Change Impacts: Droughts Floods Extreme weather events Social Impact on Rural Women: Vulnerability Livelihoods disruption (agriculture, food security) Gender inequalities Increased workload Health risks (malnutrition) Safety risks (displacement, gender-based violence) Women's Agency: Knowledge of resource management Resilience Solutions: Empowering rural women Education and skills training Access to resources Addressing gender inequalities .

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The assessment on the plant biodiversity was carried out during February 2024 to June, 2024 in Rakab Forest at Keshargarh in Purulia district, West Bengal, India. A total of 123 plant species were recorded from the study area. Among them one family was gymnosperm and all other families were angiosperms. Among those angiospermic families Fabaceae comprises highest number of species i.e.14 species, followed by Apocynaceae comprises 11 species, Asteraceae comprises 09 species, Euphorbiaceae, Lamiaceae and Poaceae contributes 05 species of each. In the present study, the conservation status of the plant specimens, given by IUCN has been mentioned. According to the information provided by IUCN, 55 species were in Least Concern(LC), 01 species was in Data Deficient(DD), 02 species were in Near Threatened (NT) and 01 species was in Endangered(EN) categories among the plants collected from the study area. This work was accomplished by collection, documentation, identification and description of the plant specimens.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Angiosperms, Diversity, Conservation status, Rakab Forest, Purulia.

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Creative Commons Attribution 4.0 and The Open Definition