Volume 13 | Issue 3 |

 Abstract

Fundus diseases are the main cause of vision loss.Doctors use special images called fundus images to classify these diseases. Computers can help with classifying using a technology called deep learning. While deep learning techniques like CNN do not effectively remove noise. To overcome the above limitations, we introduce a hybrid model combining CNN and R-FCN. In this model, we pass the fundus images through a Convolutional Neural Network to capture a variety of low-level (edges and textures) and high-level (shapes and patterns) features that are fundamental for identifying diseases in the fundus. It is applied to feature maps developed in CNN and incorporates a mechanism of position-sensitive score map to enhance the detection of regions of interest in the image, such as lesions or vascular abnormalities in retinal images. Further, it enhances the architecture using layers of convolutions for hierarchical features in images followed by a Region Proposal Network, which creates candidate regions for classification. These regions are then classified using a set of fully connected layers, making the system highly capable of localizing and classifying retinal conditions. This innovative approach can detect disease earlier and suggest for best treatment. This paper enhances the accuracy of up to 98% in Fundus image classification.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Fundus Images, Retinal Disease Classification, Deep Learning, Region-based Fully Convolutional Networks, Position- Sensitive Score Maps, Diabetic Retinopathy, Glaucoma, Age-related Macular Degeneration, Image Classification, Precision, Recall, F1-Score.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The "Smart Polyhouse Irrigation System" facilitates the growing environment and integrates several enabling technologies to tackle issues in modern agriculture. With its assistance, crops are produced and irrigation is completed without the need for humans to participate. This system additionally includes an innovative function which enables the automated upper shelter of the Polyhouse building to be adjusted in real time as needed. The setup makes it simpler to moderate conditions around the bass plants by altering the lighting, temperatures, and humidity levels to correspond with their needs. Via the use of sensor technologies, the Internet of Things, and especially intelligent business process modeling, this system conserves water as well as assets while increasing crop production with minimal manual intervention. This technological advancement in agriculture promotes environmentally friendly agriculture.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

High-Tech Polyhouse Irrigation Systems, Automatic Shelter Modification, Counter IoT Devices Smart Agriculture, Cloud-Based Crop Management Systems, Eco Friendly Agriculture Technology

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

This study examines Generation Z's preferences for online food ordering platforms, focusing on Swiggy and Zomato in Vadodara. Key factors analyzed include pricing, discounts, promotional offers, delivery speed, hygiene, safety measures, and value for money. Data was collected from 324 respondents and analyzed using Chi-Square and ANOVA tests. Results indicate that pricing and promo codes significantly influence platform preference, while factors like hygiene, delivery speed, and gender show no strong association. Income levels impact perceptions of timeliness and promotional offers but not hygiene concerns. The study suggests that Swiggy and Zomato should enhance pricing strategies, personalized promotions, and delivery efficiency to better meet Generation Z's expectations.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Generation Z, online food ordering, Swiggy, Zomato, consumer preferences, pricing, discounts, promotional offers, delivery speed, hygiene, value for money

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Diabetes mellitus characterised by hyperglycaemia is a metabolic disorder which results due to inadequate secretion of insulin (Type-I) or increased resistance to insulin by cells (Type-II). If not control the diabetes mellitus can lead to fatal complications including cardiovascular diseases, renal disease, retinal damage, foot problems and increased susceptibility to infection. Many of the oral hypoglycaemic agents are available for the effective control of blood glucose levels. This article describes the novel Dipeptidyl-peptidase-4 (DPP-4) inhibitor- Evogliptin. Evogliptin is safe and effective in the treatment of diabetes mellitus, the pharmacokinetic, mechanism of action, adverse effect, contraindication and drug-drug interactions are well explained in this review article.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Diabetes mellitus, Evogliptin, Mechanism of action

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Job satisfaction and motivation are pivotal factors influencing the performance and retention of employees in any profession. For medical representatives, whose work involves promoting pharmaceutical products to healthcare professionals, these factors are particularly significant in a competitive and demanding industry. This paper examines the relationship between job satisfaction and motivation among medical representatives, focusing on how these elements impact their work performance, career longevity, and overall well-being. The study identifies key factors contributing to job satisfaction, including compensation, recognition, work-life balance, and opportunities for career growth. Additionally, it explores the various intrinsic and extrinsic motivators, such as financial incentives, personal fulfillment, and autonomy, that drive medical representatives to perform effectively. The findings suggest that medical representatives who experience high levels of job satisfaction and motivation are more likely to achieve sales targets, build strong professional relationships, and remain committed to their roles. By understanding the dynamics of job satisfaction and motivation, pharmaceutical companies can develop strategies to enhance employee engagement, reduce turnover, and foster a supportive and productive work environment. The results highlight the importance of addressing both the tangible and psychological aspects of motivation to ensure sustained high performance and career success in the field of medical representation

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Job Satisfaction, Motivation, Medical Representatives, Performance Retention, Pharmaceutical Products, Healthcare Professionals, Compensation Recognition, Work-life Balance

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

This study explores the concept of brand loyalty concerning TVS products, with a particular focus on consumers in Tirupur City. The research aims to understand the factors influencing brand loyalty, such as product quality, pricing, after-sales service, brand reputation, and customer satisfaction. The study also examines how emotional attachment, trust, and consistent brand experience contribute to customer retention. Primary data was collected through structured questionnaires distributed to TVS product users in Tirupur, while secondary data was gathered from journals, articles, and company reports. The findings highlight the key drivers of brand loyalty, the level of customer satisfaction, and the impact of marketing strategies on consumer behavior. This research provides valuable insights for TVS Motors to enhance their brand positioning and strengthen customer relationships, ultimately fostering long-term loyalty.

Licence: creative commons attribution 4.0

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Brand Loyalty, TVS Products, Customer Satisfaction, Brand Reputation, Consumer Behavior.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The present study focuses on the Formulation and evaluation of a mesalazine mucoadhesive and ph-dependent colon-targeted drug delivery system for the effective management of inflammatory bowel diseases. The objective was to ensure minimal drug release in the stomach and small intestine while providing a controlled, targeted release in the colon. Various batch formulations were prepared using different ratios of mucoadhesive polymers such as pectin etc and ph-dependent polymers such as carbopol 940 to achieve this Colon Targeted Drug Delivery system. The selection criteria emphasized achieving minimal drug release in the first 4-5 hours to bypass the stomach and small intestine and provide protection from upper GIT, followed by a significant release after 5-6 hours for precise colon targeting. Dissolution studies were conducted on nine batches to determine the release profile. Among the tested formulations, Batch 6,7,8 and 9 demonstrated minimal release during the initial 5 hours and a gradual, sustained release thereafter. Batch B3, B6 and B9 showing a higher mucoadhesion profile. Batch 9 the optimal candidate for ph-dependent colon-targeted delivery and as well as muchoadhesion, ensuring effective site-specific drug release. However, Batch 9 stood out with a superior balance of controlled release with high muchoadhesion, confirming its suitability for colon targeting. In contrast, Batches 1, 2, 3, 4, and 5 showed premature drug release within the first 3-4 hours and batch B6, B7 and B8 it's a showing less mucoadhesive profile compare to batch 9 failing to meet the criteria for ph-dependent delivery and mucoadhesive properies. The study concludes that Batch 9 is the best formulation for a mesalazine mucoadhesive and ph- dependent colon-targeted drug delivery system, offering enhanced therapeutic efficacy and reduced systemic side effects in the treatment of colonic disorders. This optimized system leverages controlled release technology to address the limitations of conventional therapies.Further investigations, including in vivo studies, are recommended to validate the in vitro findings and confirm the clinical potential of this formulation. The promising results from this study the way for advanced, targeted drug delivery systems for chronic gastrointestinal diseases.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Mesalazine, pH-dependent drug delivery, Colon-targeted tablets, Carbopol 940, Pectin, Compression coating, Inflammatory bowel disease, Delayed release, Mucoadhesion te

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

This paper presents the design, development, and performance evaluation of an Arduino-based Digital Light Processing (DLP) resin 3D printer, focusing on creating an affordable, open-source alternative to commercial resin printers. The system utilizes an Arduino Nano microcontroller to control a combination of UV LEDs and an LCD masking screen, enabling precise photopolymer resin curing. Key features include custom firmware for stepper motor control, optimized UV exposure techniques, and cost-effective hardware integration. Results from cutting edge experiments clearly show printers of unmatched quality and superior usefulness of materials with big cost savings that are huge. The study brings things to a close highlighting some really cool ways this thing could be put to use and proposing some awesome ways to mix things up and make that thing even better

Licence: creative commons attribution 4.0

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Arduino Nano, Digital Light Processing (DLP), Resin 3D Printer, UV Curing, Open-Source Hardware, LCD Masking Technology, Stepper Motor Control.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Conjunctiva is a translucent mucous membrane which lines the anterior aspect of eyeball and posterior surface of the eyelids where subconjunctival haemorrhage is small petechial haemorrhage to an extensive one spreading under the whole of bulbar conjunctiva, when a tiny blood vessel in the conjunctiva bursts on its own, resulting in a red patch on the sclera.1 Arjuna which comes under Shuklagata Roga. Arjuna shows symptoms Niruka-Shasharudhira-prakash Bindu (redness of eye without pain).2 Reviewing the clinical presentation from modern texts it is found that resembles with Subconjunctival haemorrhage. An ocular therapeutic called Bidalaka is the application of medicated paste on the eye's outer surface expect eyelashes.3 Bidalaka is indicated in inflammatory conditions of the eyes. A 29-year-old female patient diagnosed with Subconjunctival haemorrhage on clinical presentation was advised Yashti Triphala Bidalaka and Vasa Guduchyadi Kashaya as internal medicine for 10 days. The signs and symptoms were reduced to mild degree. The result proved to be effective based on clinical assessment.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Arjuna, Subconjunctival haemorrhage, Case study, Shuklagata Roga, Bidalaka, Kriyakalpa.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

he "Make in India" initiative, launched in 2014, has significantly impacted India's global economic standing by fostering manufacturing growth, attracting foreign investments, and enhancing employment opportunities. This research paper evaluates its influence on key sectors, policy reforms, and infrastructure development. Case studies on mobile manufacturing, the automobile industry, and defense production highlight the initiative's success. Challenges such as infrastructure bottlenecks and skill shortages are discussed, along with potential areas for improvement. The paper also examines the future prospects of "Make in India" in shaping India's role as a global manufacturing hub. Insights from government reports, industry data, and economic analysis support the findings.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Make in India, Economic Growth, FDI, Manufacturing, Exports, Employment, Global Economy

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Creative Commons Attribution 4.0 and The Open Definition