Volume 12 | Issue 12 |

 Abstract

From time to time, many social reformers emerged in India and they made every effort to remove the prevailing evils of the society. There is a big difference between the new social reform movements of India and the ancient movements. The main objective of the movements of kabir, ramanuja etc. Was also to remove the evils of the society but their movements were completely indigenous. But most of the social reformers who emerged in India in the beginning of the 19th century were influenced by western civilization and wanted to reconstruct the Indian society on that basis. The movements of brahma samaj and raja ram mohan roy were completely inspired by western civilization. But the movements of arya samaj and ramakrishna mission were indigenous in their basic spirit. These social reform movements laid the foundation of social and religious renaissance of India and paved the way for the national movement.

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Key word- Raashtreey Aandolan, Aary Samaaj, Brahm Samaaj, Dhaarmik Sudhaar, Jaatipratha

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Abstract The cholesterol degrading bacteria were isolated and characterized from the vegetable oil industrial wastes of Buldhana District. thirteen strains were isolated by the primary screening. Among the thirteen, only two strains were identified as cholesterol oxidase enzyme producers. The morphological and biochemical characters revealed that the isolated microorganisms were Pseudomonas sp., and Bacillus sp. The isolated microorganisms were grown in a cholesterol medium and their degrading potency of cholesterol was determined by TLC. The cholesterol oxidase (CHO) extracted from the isolates was partially purified. The present study revealed that the isolates (Pseudomonas sp., Bacillus sp.) isolated from the industrial wastes had good cholesterol degrading potential and would be considered as good source of CHO for important medical applications.

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Keywords: Bioconversion, cholesterol degrading bacteria, cholesterol oxidase, vegetable oil waste.

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Abstract In the present study samples were collected from various agricultural dumping sites of Shegaon Dist. Buldhana, Maharashtra, India and two strains of Actinomycetes were isolated from these samples. Actinomycetes produces several hydrolytic enzymes which is helpful for degradation of solid waste, further the isolates were identified as Actinomycetes on the basis of morphological and biochemical studies. These strains were selected on the basis of primary screening of strains. Cellulolytic activities were confirmed by formation of clear zone of hydrolysis around the colonies.

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Keywords: Cellulase, Actinomycetes, cellulolytic activities.

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Flowers please the mind and grant prosperity. Flowers are at the epicentre of Indian culture for every occasion, Indians use flowers to decorate doors. Varmala, (A garland a bride puts on the bridegroom's neck during marriage ceremony) to different ornaments for various occasions are a part of ancient ayurvedic texts. The Indian woman loves to adorn herself; she has always worn flowers in her hair with since Vedic era. In southern India even today, women wear flowers in their hair regularly. From the epic Ramayana to Gita, flowers are an eternal part of Indian culture. A sight to behold is the Temple's God and Goddess idols always ornamented with flowers, an offering wholeheartedly given by worshippers and accepted by God, that is the Hindu belief. To use flowers to personal beautification is noted in ancient ayurveda texts. These flowers also have a spiritual significance. Goddess Laxmi sits on a lotus. In kalidasa's Abhijnana Shakuntala. Shakuntala is compared to the delicate jasmine flower. Her accessories were flowers and leaves. In another work of Kalidasa Meghduta, it is mentioned that the powder of Lodhara flowers was applied as face powder. The Mallika flowers have been used by women to promote wellness and beauty. The Indian culture gives a lot of importance to flowers. Goa has many temples and several are famous for stunning decorations with flowers on and around the idol. This trickles down to the local community who work in the vicinity of these temples. A sustainable cycle of flowers which the flower ladies, devotees and the priest comply with.

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History, Goa, Flowers, Flower craft, Hair accessories, Temple, Sustainable.

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Bone is a metabolically active organ. Excessive stress or traumatic accidents may cause fractures, and diseases like Osteoporosis and osteomalacia lead to the weakening of bones respectively which further causes defects in them. Although bone has a high capacity for healing, large bone defects cannot be self-healed. They need various surgical interventions such as joint arthroplasty or bone grafting. Such surgical procedures can heal the defect but may cause inflammation at the surgical site, infection, donor-site morbidity, and various other limitations. To avoid these post-surgical problems a three-dimensional bioprinting (3D) of bone tissue is introduced. In this technique, a bone scaffold of precise size and shape is engineered with the help of bioinks comprising suitable biomaterials, cells, and growth factors. This bone scaffold is then implanted in the patient's body through surgical procedures. Bone scaffolds, bio-inks, and growth factors are the important elements of this technique. This technique enables us to construct personalized scaffolds according to patients' needs. High-accuracy simultaneous printing of cells with scaffolds is one of the advantages of 3D printing. In this review, bone defects have been discussed followed by an introduction to 3D bioprinting and its type. Later the following review emphasizes the process of bone tissue bioprinting and the properties of an ideal bone scaffold. Bioinks and the composition used for the process and various growth factors involved in it are mentioned. And at last, the current challenges of 3D bioprinting in the treatment of bone defects in humans were also acknowledged.

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: Scaffolds, Bio-inks, GelMa, Bone Regeneration, Bio-compatibility, Extrusion-based Bioprinting, Ink-jet Bioprinting, Laser-assisted Bioprinting, Stereolithography Bioprinting

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Bioavailability refers to the fraction of administered drug that reaches the systemic circulation in an unchanged form and is available to exert its therapeutic effects. It is the rate and extent to which a drug is absorbed from its dosage form and becomes available at the site of action. Bioavailability and bioactivity both the concepts are related to the effectiveness of drugs. The term pharmacological response is directly related to our body's blood plasma levels. Thus, bioavailability is defined as the rate and extent (amount) of absorption of an unchanged drug from its dosage form. An ideal drug must have to live within the body and must not reform the properties of biomolecules apart from target molecules. Nano drug delivery systems, also known as nanocarriers or nanomedicines, refer to a class of pharmaceutical formulations that utilize nanotechnology to deliver drugs or therapeutic agents to specific target sites within the body. Nanotechnology offers precise control over the design and fabrication of drug delivery systems. By encapsulating drugs within nanoparticles or nanocarriers, their stability, solubility, and targeted delivery can be improved. Nanoparticles can protect drugs from degradation, enhance their absorption, and enable controlled release, thus improving bioavailability. Nanoparticles can be engineered to specifically target diseased cells or tissues while sparing healthy ones. Functionalized nanoparticles can be designed to attach to specific molecules or receptors found on cancer cells, for instance. This targeted approach reduces systemic side effects and enhances the bioactivity of therapeutic agents.

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Keywords: Nano Drug delivery system, Bioavailability, Nanocarriers, Bioactivity, Nanotechnology.

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India's agriculture faces challenges such as diverse climates, fragmented landholdings, and the need for sustainable practices. To address this, we propose an intelligent support system using data analytics to offer personalized crop recommendations, disease identification, and fertilizer suggestions. Built on a comprehensive dataset from surveys of farmers across India, it captures their unique experiences and challenges.

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Crop recommendation, Machine learning,XGBoost,Plant disease identification,Fertilizer

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This research discusses the application of Primavera software in financial integration and project management in the construction of residential buildings. The study puts more emphasis on how the sophisticated scheduling, resource allocation, and financial monitoring capabilities of Primavera may enhance project efficiency and cost control. The case study demonstrates how improved teamwork, real-time tracking of progress, and efficient budgeting procedures may reduce delays and cost overruns. This approach emphasizes the importance of including it integrates technology into construction management and gives guidelines for improving project results. Potential that Primavera holds to be a comprehensive solution in accurately and efficiently managing complex residence building projects is reflected upon.

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Primavera, Project management, Resource allocation, financial integration.

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Creative Commons Attribution 4.0 and The Open Definition

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Uttar Pradesh Ki 14vi se 17vi Vidhansabha me vipaksh ke prabhav ka moolyankan : Rajnitik Gati aur Samarthan ki Disha

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The gut microbiota, a complex ecosystem of trillions of microorganisms residing in the gastrointestinal tract, plays an integral role in maintaining human health. Recent advancements in neuropsychobiology suggest that this microbial community profoundly influences mental health, particularly anxiety and depression, via the gut-brain axis. This paper investigates the intricate bidirectional communication between the gut microbiota and the central nervous system (CNS), mediated by neural, endocrine, immune, and metabolic pathways. Emphasis is placed on mechanisms such as microbial metabolite production, vagus nerve signaling, hypothalamic-pituitary-adrenal (HPA) axis regulation, and neuroinflammatory responses. The potential therapeutic applications of probiotics, psychobiotics, prebiotics, and dietary interventions are explored, along with emerging technologies in microbiome research. Challenges such as individual variability, ethical constraints, and the need for longitudinal studies are also discussed. This review aims to provide a comprehensive understanding of the gut microbiota's role in mental health, emphasizing the need for integrative therapeutic approaches to tackle anxiety and depression.

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 Keywords

Gut-brain axis, gut microbiota, mental health, anxiety, depression, psychobiotics, probiotics, prebiotics, SCFAs, dietary interventions, gut-brain communication, neuroinflammation, HPA axis, neurotransmitters

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Creative Commons Attribution 4.0 and The Open Definition