Volume 12 | Issue 12 |

 Abstract

Transferosomes are elastic substances that can bend their structure and squeeze themselves through narrow pores smaller than their size, making them an effective drug delivery mechanism for poorly soluble medicines. They are ultra-deformable vesicles with a hydrophilic core in the center and a lipid bilayer around them. To address the challenges with conventional oral drug delivery, alternative formulations of transferosomes have been created employing non-ionic surfactants such Span 80, Span 20, soya lecithin, Carbopol 940, and Tween 80 by rotary film evaporation and Vortexing/sonication processes.This carrier system has piqued the interest of pharmaceutical researchers because it improves patient acceptability and reduces side effects associated with the traditional oral route by avoiding first-pass metabolism, thereby improving the physiological and pharmacological response through consistent drug levels. This review covers the structure, benefits and drawbacks of formulation materials, formulation procedures, evaluation techniques, and applications, as well as patents published in the literature.

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 Keywords

Transferosomes, Lipophilic, Medication, Skin, Epidermis.

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Creative Commons Attribution 4.0 and The Open Definition

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Mosquito-borne diseases remain a significant global health concern, necessitating effective and safe repellent solutions. This study explores the formulation of a gel-based mosquito repellent using extracts from Tridax procumbens (coat buttons), Cymbopogon citratus (lemongrass), and Azadirachta indica (neem). These plant species are known for their potent insect-repellent properties, attributed to compounds such as pyrethrins, citronella, and azadirachtin, respectively. The gel formulation was developed through a systematic extraction process followed by optimization of ingredient concentrations to enhance efficacy and stability. Physical and chemical characterization included viscosity measurements, pH determination, and stability testing under varying environmental conditions. In vitro testing against mosquito species known to transmit diseases such as malaria and dengue demonstrated significant repellent activity compared to control formulations. Furthermore, skin compatibility studies using human volunteers indicated minimal irritant potential, supporting its suitability for topical application. Overall, this mosquito repellent gel represents a promising alternative to synthetic repellents, harnessing the natural repellent properties of Tridax procumbens, Cymbopogon citratus, and Azadirachta indica while ensuring safety and efficacy for public health applications.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Mosquito Repellent, Polyherbal Gel, Tridax Procumbens, Cymbopogon Citratus, Neem

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The fourth industrial revolution and its Industry 4.0 or connected industry technologies dominate the current production research discussion. Digital developments like cyber-physical Systems are the key technologies for future, more agile production systems, but a common understanding of the term Industry 4.0 is not established now. First generic implementation approaches present manifold technical solutions but need to be integrated with existing Lean Production Systems. The actual impact of Industry 4.0 solutions is mostly not specified, and a method to evaluate is missing. This paper introduces Industry 4.0 in an environment of connectivity in the Internet of Things and Services with the vision of a smart factory. Lean Production Systems and Lean Principles characterize the initial situation of industrial companies. Industry 4.0 offers an estimated benefit for companies by stabilizing Lean processes with Industry 4.0 applications. To support the development process the presented Concept of an Industry 4.0 impact matrix on lean production systems gives a useable framework. The matrix considers elements of lean production systems with Industry 4.0 technologies and estimates impact first. In the described development process of a cyber-physical Just-in-Time delivery, the matrix is used to find a stabilizing application for a Just-in-Time material supply process.

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 Keywords

1. Introduction 2. Related works and terminology3. Systematic literature review 4. Field study on Lean Production Systems 4.0 5. Discussion 6. Conclusions

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Creative Commons Attribution 4.0 and The Open Definition

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We have used Artificial Intelligence process for solving the fuzzy games containing Octagonal, Pentagonal and Hexagonal fuzzy numbers. This process is decision making process in the logic forms. We have made optimum solution of fuzzy game theory problems having, octagonal, pentagonal and hexagonal fuzzy numbers. In this case new ranking was used to order any fuzzy numbers. This is logical decision makers game theory for the study of mathematical models. In this solution a game situation involving a set of players who have a set of possible choices and in which outcome for any individual player depends partially on the choices made by the other players.

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Creative Commons Attribution 4.0 and The Open Definition

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Artificial Intelligence, Fuzzy game, octagonal, pentagonal, hexagonal, fuzzy number, optimum solution.

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Creative Commons Attribution 4.0 and The Open Definition

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The principles of quality assurance (QA) and quality control (QC) are crucial for maintaining the integrity of drug manufacture and delivery in the pharmaceutical sector and go beyond simple regulatory requirements. QA includes the design, development, production, and service processes as well as any other systematic methods required to give assurance that a product meets quality standards. It is a proactive procedure intended to stop mistakes and flaws in manufactured goods. Contrarily, QC is the area of quality management that is concerned with meeting quality standards. The methods and procedures utilized to meet quality standards are included in this operational methodology. QC is primarily the inspection component of quality management, whereas QA is mainly concerned with the way a process is carried out or a product is manufactured. When combined, QA and QC not only help ensure that rules and regulations are followed, but they also provide the basis for creating medications that are safe, efficient, and dependable for both patients and medical professionals. This review paper explores the complexities of quality assurance and quality control in the pharmaceutical industry, emphasizing their vital functions and the influence they have on the healthcare system as a whole.

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Keywords: Quality Control, Quality Assurance.

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Creative Commons Attribution 4.0 and The Open Definition

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This study investigates the relationship between agricultural trade and agricultural GDP in India during 1990-91 to 2022-23. This study uses the ADF unit root test, Johansen cointegration and granger causality test to investigate the long run causality between export, import and Gross domestic product in the model. All data related to agricultural sector only. The first difference of the variables is found to be stationary and hence LNAGDP, LNAEXP and LNAIMP are integrated of order one I (1). Based on the trace statistic and Eigen value, there existed long run relationship between agricultural trade and agricultural GDP. The nature and direction of relationship between agricultural export, import and agricultural GDP was examined by applying Johansen cointegration test and Granger causality tests. The obtained results showed that there is unidirectional causal relationship from AgriGDP to agricultural export, agricultural GDP to agricultural import and export to import at 5% significance level, while no causality relationship exist from import, export to GDP and import to export. It means AGDP lead to export but Agri export does not lead to AGDP

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

causality, agricultural export, cointegration, AGDP

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Creative Commons Attribution 4.0 and The Open Definition

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Bottom ash is a byproduct of coal combustion in thermal power plants, it is characterized by its granular texture. The composition of bottom ash includes silica (SiO2), alumina (Al2O3), and iron oxide (Fe2O3). Bottom ash is used only as a filler material in construction Industry. In this study we used bottom ash waste as a proxy material to reduce the increasing cost in the construction industry. Coal bottom ash waste generated each year in high volume. This paper reviews the physical and chemical characteristics and utilization of coal bottom ash as a proxy material in the construction industry. The goal of this review is to emphasize the possibility of recycling of bottom ash in civil construction.

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 Keywords

- Bottom Ash Concrete, Coal Bottom Ash, Concrete Mix Design, Thermal Power Plant (TPP), Sustainable Concrete, Compressive Strength, Cement, Sand and Aggregate.

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Creative Commons Attribution 4.0 and The Open Definition

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India is taking path breaking measures toward securing its energy future by embracing sustainable practices like ethanol blending. Being one of world's major energy consumer, the country has traditionally depended on oil imports to meet its growing energy needs. This dependence poses challenges to energy security and leads to a substantial outflow of foreign currency. However, with ethanol blending, India has a defining opportunity to reduce its dependence on imported oil while addressing environmental concerns. Ethanol, a byproduct of sugarcane processing when blended with petrol, cuts down on fossil fuel consumption and reduces harmful carbon emissions which adversely affects climate change and causes public health issues. The practice of blending ethanol with petrol began in 2001 on a pilot mode. Yet, for many years, progress was slow, and ethanol production remained stagnant. In recent years the Govt. Of India initiated a series of comprehensive reforms , as a result of which India has been able to unlock the full potential of this initiative. These reforms are now driving substantial outcomes, not just by enhancing energy security, but also by revitalizing rural economies. Ethanol production offers a new source of income for farmers, supporting the agricultural sector and fostering economic growth in rural areas. The Government's has taken ambitious target of increasing the ethanol blending to 20% from earlier set target of year 2030 to year 2025, demonstrating a strong commitment. During the 7th G-STIC Delhi Conference, Shri Hardeep Singh Puri, Minister of Petroleum and Natural Gas, emphasized India's growing success in ethanol blending and its broader commitment to sustainable energy solutions. This forward-looking approach indicates that India is not only focused on meeting its immediate energy needs but is also preparing for long-term sustainable energy solutions to address future demands.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Ethanol Blending , Fossil Fuel, Feedstock , Biofuel , Interest Subvention

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Creative Commons Attribution 4.0 and The Open Definition

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The "Coolie" website is an innovative platform designed to connect individuals and businesses with skilled laborers for hire. Inspired by the UrbanClap model, the platform addresses the need for a streamlined, user-friendly solution for booking labor services across various domains. The website offers an intuitive interface where users can browse, select, and book skilled laborers based on their requirements, such as electricians, plumbers, carpenters, and more. Features include real-time availability, secure payment integration, user reviews and ratings, and an efficient booking management system. "Coolie" aims to bridge the gap between service providers and customers by ensuring transparency, reliability, and convenience. By leveraging modern web technologies, the platform aspires to enhance user experience while creating employment opportunities for skilled workers. This project demonstrates practical implementation of web development skills, database management, and user experience design, catering to real-world needs.

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Creative Commons Attribution 4.0 and The Open Definition

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skilled laborers for hire, UrbanClap-inspired platform, labor services booking, user-friendly interface, real-time availability, secure payment integration, user reviews and ratings, booking management system,

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Creative Commons Attribution 4.0 and The Open Definition

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A green bond is a debt security that raises money from investors to fund projects that are environmentally or socially beneficial. A green bond is an investment avenue for investors to provide investments and funding for environmental friendly projects. Green bonds are used to finance or refinance projects that contribute to the welfare of environment or climate, such as renewable energy, energy efficiency, sustainable waste management, and clean transportation

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Creative Commons Attribution 4.0 and The Open Definition

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GREEN BOND INVESTMENT

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Creative Commons Attribution 4.0 and The Open Definition