Volume 12 | Issue 12 |

 Abstract

INTRODUCTION: Leprosy or Hansen's disease is a chronic granulomatous disorder that is caused by Mycobacterium leprae. It mostly affects skin and peripheral nerves. The disease has varied clinical and pathological manifestations depending on the immune response of the patient. It still remains as a major public health problem facing India. Nearly, 60% of all world leprosy cases are reported from India. The spectrum of presentation of leprosy is very wide. Histopathology is an important tool, helps in confirming the diagnosis for clinically suspicious cases and helps in exact typing which, in turn, influences treatment plan. AIMS AND OBJECTIVES: To study the histopathology of Leprosy cases and identify different Histological subtypes of leprosy at SBKS MIRC sumandeep vidyapeeth , dhiraj hospital, pipariya, waghodiya, vadodara. METHODOLOGY: A retrospective hospital-based study of clinically diagnosed leprosy cases was conducted over a period of 3 Years (January 2020 to January 2023). Lesional skin biopsies obtained were fixed, processed and stained with Haematoxylin and Eosin (H&E) and Fite - Faraco (FF) staining for demonstrating lepra bacilli. The lesions were classified on microscopy as per Ridley-Jopling classification. RESULTS: A total of 100 cases were studied. Highest incidence was in 3rd decade of life. Males were more affected. Most common clinical feature was loss of sensation. The commonest reported histopathological type was tuberculoid leprosy followed by lepromatous leprosy. The concordance was highest in histoid leprosy, indeterminate leprosy and Type 1 Lepra reaction. Overall FF staining was positive in cases. CONCLUSION: The Histopathological examination plays an important role in making definite diagnosis. It still remains the gold standard for early accurate diagnosis and typing of leprosy. Accurate diagnosis is required for proper treatment, preventing deformities and drug resistance. Histopathology also useful for monitoring treatment response.

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Leprosy, Histomorphology, skin biopsy, Mycobacterium leprae, Hansen's disease

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The Bodhisattva ideal, a cornerstone of Mah?y?na Buddhism, embodies selfless compassion and the commitment to alleviate the suffering of all beings. In modern times, this ideal transcends traditional monastic settings, finding relevance in addressing contemporary global challenges such as social inequality, environmental degradation, and ethical crises. This paper explores the application of the Bodhisattva ideal in diverse modern contexts, including social activism, education, healthcare, and environmental conservation. It highlights the transformative potential of this ancient ethical framework when integrated into secular domains, emphasizing the cultivation of compassion, wisdom, and interconnectedness. Through an analysis of contemporary movements and individual case studies, the research underscores how the Bodhisattva ideal inspires meaningful action and fosters resilience in the face of adversity. Additionally, it examines the challenges of adapting this ideal in a rapidly changing world while maintaining its spiritual integrity. The paper concludes by proposing strategies to further enhance the practical application of the Bodhisattva ideal, positioning it as a timeless guide for personal and societal transformation in the 21st century. `

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Bodhisattva, Buddhahood, Perfections, Skillful Means...

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Doordarshan Vigyapano Ka Kishor Vidhyarthiyo Ke Samajik Av Sanskrutik Vikash Per Padnewale Prabhav Ka Adhyan

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Doordarshan Vigyapano Ka Kishor Vidhyarthiyo Ke Samajik Av Sanskrutik Vikash Per Padnewale Prabhav Ka Adhyan

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Farmer Producer Organizations (FPOs) act as a catalyst for enhancing the economic stability of small and marginal farmers by promoting collective action. They help farmers in accessing markets efficiently, securing better prices, and minimizing exploitation by middlemen. FPOs leverage economies of scale to streamline input procurement and production, which subsequently reduces costs and boosts the income of members. FPOs also focus on value addition and market linkages by encouraging processing and packaging of agricultural products. They provide essential training programs that lead to increased returns for farmers. Additionally, FPOs facilitate access to financial services and credit, thereby reducing credit risks for individual farmers. These organizations empower farmers by representing their interests in policy-making processes, ensuring the formulation of favorable policies for economic development. Through various initiatives such as risk mitigation, reduction in post-harvest losses, and promotion of sustainable farming practices, FPOs contribute to the overall economic stability of farmers, fostering resilience and sustainability in agriculture.The article highlights the pivotal role of FPOs in improving the economic stability of farmers through collective strength, better market access, financial services, and sustainable agricultural practices. Ultimately, these efforts can lead to increased income and economic resilience among the members.

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Aggregation of Produce; Grant and Subsidy Access; Hub and Spoke Model; Information Exchange

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Most Ayurvedic practitioners work in rural areas, providing health care to at least 500 million people in India alone. These herbal medicines dominate the practice of Ayurveda. Biodiversity is the main source of human survival & financial wellbeing on which the whole people, families, communities, nations and future generation depends. Medicinal plants are globally valuable sources of herbal products and they are disappearing rampantly. Therefore, with proper care and management biological sources can be used sustainably ensuring their use for our forthcoming generation

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Promote Ayurveda to protect the Plants: A case study

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Abstract-- Groundwater depletion and contamination are pressing challenges threatening global water security and sustainability. Conventional educational methods for promoting groundwater conservation often fail to engage diverse audiences effectively. This study introduces an interactive educational game leveraging Q-learning, a reinforcement learning algorithm, to teach optimal groundwater management practices. The game simulates real-world scenarios, including drought, contamination, and resource allocation, offering a dynamic and personalized learning experience for players across age groups. The system dynamically adjusts question difficulty based on player performance, fostering sustained engagement and knowledge retention. Developed as a web-based platform using Django and SQLite, the game integrates a leaderboard, quiz-based gameplay, and adaptive question progression. By combining gamification and reinforcement learning, this system empowers individuals to make informed decisions about water resource management, contributing to broader efforts in environmental education and sustainable development.

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Keywords-- Groundwater conservation, environmental education, Q-learning, reinforcement learning, gamification, quiz-based learning, adaptive difficulty adjustment, scenario-based learning, sustainable water management, resource management simulation, web-based application, water resource sustainability.

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This study explores the transformative role of Artificial Intelligence (AI) and automation in Human Resource (HR) practices, focusing on enhancing efficiency, employee well-being, and organizational performance. It examines key areas such as employee productivity measurement, payroll automation, real-time feedback, and health and safety improvements. A conceptual framework is proposed to understand AI's impact on HR digitization, organizational design, and network analysis. Through literature review and empirical research, the study highlights AI's potential to revolutionize HR processes while addressing associated challenges.

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Artificial Intelligence, HR Automation, Employee Productivity, Real-time Feedback, Organizational Design, Payroll Automation, Workplace Safety.

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Template matching has proven valuable in the field of medical imaging and document analysis, where it aids in verifying document authenticity, identifying structures in images, and categorizing records efficiently. This paper introduces a Medical Insurance Document Verification System (MIDVS), designed to meet the specific demands of medical document and image verification. Using an integrated approach, which includes region-ofinterest (ROI) extraction, structural similarity index (SSIM) analysis, and optical character recognition (OCR), MIDVS achieves precise matching even under variations in document layout or image conditions. The results demonstrate MIDVS's potential in improving processing accuracy and reliability for large-scale medical document management and verification.

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medical insurance, medical based insurance system, fraud insurance detection, insurance detection

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This study explores the impact of employee remuneration benefits on performance, job satisfaction, and organizational productivity. By analyzing empirical and theoretical frameworks, the research identifies the significance of wages, salaries, bonuses, and incentives in enhancing employee motivation and retention. The findings suggest a positive correlation between effective remuneration policies and improved organizational outcomes. Recommendations for policy implementation are provided.

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Remuneration, Salaries, Wages, Bonuses, Incentives, Employee Performance, Organizational Productivity

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Flavonoids represent a diverse class of plant-derived compounds with significant therapeutic potential. This review focuses on two prominent flavonoids, rutin and chrysin, examining their biochemical properties, mechanisms of action, and therapeutic applications. Rutin, a glycoside of quercetin, demonstrates notable antioxidant, anti-inflammatory, and vasoprotective properties, with promising applications in cardiovascular disease, diabetes management, and neuroprotection. Chrysin, a naturally occurring flavone, exhibits anticancer, anti-inflammatory, and anxiolytic effects through multiple cellular pathways, including modulation of apoptosis and inflammation mediators. Recent evidence suggests both compounds may have synergistic effects when combined with conventional treatments. This review synthesizes current research findings, highlighting the molecular mechanisms underlying their biological activities and discussing challenges in their clinical application, including bioavailability and delivery systems. Understanding these flavonoids' therapeutic potential could lead to innovative treatment strategies for various pathological conditions.

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Flavonoids, Rutin, Chrysin, Anti-anxiety, Anxiolytic, Anti-inflammation, Antidiabetic.

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